We are offering a unique opportunity to join our team in the Roche Innovation Center Basel.
Preclinical Chemistry, Manufacturing and Controls is a global function within Pharma Research and Early Development (pRED). We develop robust and innovative API synthesis and drug products to supply and enable key preclinical activities paving the way towards Entry Into Human. We are CMC experts and together with our discovery functions partners, we generate scientific and technical knowledge to assess the developability of drug candidates. We build our strength on a broad diversity of enthusiastic technical experts, pharmacists, chemists and analytical chemists delivering and innovating in the space of small molecules, peptides and oligonucleotides.
In this role:
- You will be part of a team of process research, scale-up & supply chemists, purification and analytical sciences experts, supporting a diverse portfolio of small molecule, peptides and nucleic acid discovery projects. You develop synthetic routes suitable for early toxicological and clinical phase I campaigns. You are accountable for the scientific and technical excellence of the work performed within your area of responsibility
- You stay abreast of developments and trends pertinent to small molecules, peptides and nucleic acids process R&D and supply. You attend relevant conferences, build strong internal and external relationships to maintain a strategic understanding of the process R&D technology environment and recommend priorities
- As a pCMC (deputy) Project Leader, you orchestrate all preclinical CMC activities (internal and external) and ensure an efficient project transfer to Chemical Development for Phase I clinical supply of small molecules and for Phase II clinical supply of oligonucleotides and peptides projects
- You may participate in the assessment of business development opportunities
What else are we offering?
We are dedicated to support our staff in the development of their knowledge and skills and offer further career opportunities where people demonstrate talent and aptitude.
Who are we looking for?
We are seeking a committed individual who brings:
- PhD in organic synthesis with over 3 years of experience in the small molecule, peptide and/or oligonucleotide drug R&D. You possess a sound understanding of the drug development process and a good knowledge of key aspects and scientific methods used to synthesize new drug candidates
- Experience in solid phase synthesis (oligonucleotides or peptides) and/or in the scale-up & supply of new drug candidates on multi kilogram scale is a critical asset
- Experience in lab automation and/or data workflows & analysis is a key asset
- Creative thinking. You are curious and passionate about scientific and technical innovation. You can quickly learn and adapt your thinking to complex and evolving environments
- Ability to guide the work of others and operate in agile teams. You can lead and motivate others, as well as prioritize and coordinate their work through to successful outcomes
- Strong cross-functional teaming skills: you have an inclusive and collaborative way of interacting. You demonstrate good communication skills that enable you to effectively collaborate within cross-functional teams (Discovery and Technical Development Teams) and interact across interfaces (Medicinal Chemistry, Chemical Development, Toxicology, DMPK)
- Fluency in English; knowledge in German is of advantage
Are you ready to apply?
No hay comentarios:
Publicar un comentario